Comparison of antigen and antibody detection tests used for diagnosing the Helicobacter pylori infection in symptomatic patients // Basic and Clinical Sciences. 2010. <...> The role of endoscopy in the management of patients with peptic ulcer disease // Gastrointestinal Endoscopy. 2010. <...> Bertleff M. J., Lange J. F. Perforated peptic ulcer disease: A review of history and treatment // Digestive surg. 2010. 27. <...> Billing A., Frohlich D., Schildberg F. W. Prediction of outcome using the Mannheim peritonitis index in 2003 patients. <...> Risk stratification in perforated duodenal ulcers: A prospective validation of predictive factors // Ann. <...> Canoy D. S., Hart A. R., Todd S. J. Epidemiology of a duodenal ulcer perforation: a study of hospital admissions in Norfolk, United Kingdom // Digest of Liver Diseases. 2002. <...> Chiu H. S., Chung C. H. Pneumoperitoneum on supine abdominal X-ray: case report and review of the radiological signs // Hong Kong journal of emergency medicine. 2005. <...> Millat B., Fingerhut A., Borie F. Surgical treatment of complicated duodenal ulcers: controlled trial // World J. Surg. 2000. <...> Schцttker B., Adamu M. A., Weck M. N., Brenner H. Helicobacter pylori infection is strongly associated with gastric and duodenal 49 . . . ulcers in a large prospective study // Clinical gastroenterology and hepatology. 2012. 10. <...> William D., Owens M. D. American Society of Anesthesiologists physical status classification system is not a risk classification system // Anesthesiology. 2001. <...> P. N. Romashchenko, N. A. Maistrenko, A. E. Korovin, S. A. Sibirev, P. A. Sidorchuk NEW APPROACHES IN TREATMENT OF PATIENTS WITH PERFORATED DUODENAL ULCER Kirov Military Medical Academy, Saint-Petersburg The results of examination and treatment of 152 patients with perforated duodenal ulcer were analyzed with the aim to make the ground of systemic approach to their surgical treatment in consideration of contemporary achievements of laboratorial « » • 2013 and instrumental diagnostics and the opportunities of minimally invasive surgery. <...> The results of conducted clinical study showed that in order to establish the correct preoperative diagnosis and the choice of rational treatment of patients with perforated duodenal ulcer it <...>