Горького, Донецк, Украина Multifactorial mathematical model of the eff ectiveness of primary open-angle glaucoma treatment Многофакторная математическая модель эффективности лечения первичной открытоугольной глаукомы ______________________ Резюме __________________________________________________________________________ Цель данного исследования – создать многофакторную математическую модель эффективности лечения первичной открытоугольной глаукомы (ПОУГ). <...> Methods of development and analysis of the regression logistic models were used to defi ne risk factors of the treatment failure for patients with primary open-angle glaucoma, and to evaluate the direction and the level of their infl uence. <...> A multifactorial mathematical prediction model was built to evaluate the eff ectiveness of POAG treatment. <...> Восточная Европа» № 4 (23), 2014 267 Многофакторная математическая модель эффективности лечения первичной открытоугольной глаукомы INTRODUCTION In accordance with forecasts the number of patients with primary glauWhen it comes to modern concepts, the primary open-angle glaucoma is treated as a multifactorial disease with a threshold eff ect, which leads to glaucomatous optic neuropathy [7]. coma by 2020 could increase to 79.6 million people, among which 74% will have the primary open-angle glaucoma (POAG). <...> POAG occupies today a leading position in the system of eye diseases that lead to disability and ablepsia among the population worldwide. <...> The metabolic factors of glaucoma progression are not enough studied today, and the metabolic concept of pathogenesis of the glaucomatous optic neuropathy is being still investigated. <...> In this connection neuroprotection is one of the perspective directions of the glaucomatous optic neuropathy prevention and treatment [1, 3]. <...> Earlier we reported on the experimental and clinical substantiation of the use of neuroprotective therapy in POAG complex treatment [5, 6]. <...> Despite numerous researches, the problem of assessing the glaucomaThe purpose of this research is to create a multifactorial mathematical model of the eff ectiveness of POAG treatment. tous optic neuropathy progression, which patients with the primary open angle glaucoma have, as well as the treatment eff ectiveness remains unresolved. <...> Group I – patients with POAG of I-II stage and normal IOP (19 patients received the conventional treatment and a complex of neurotropic drugs, 22 – the conventional treatment). <...> Group II consisted of patients 268 Материалы Республиканской конференции с международным участием <...>