Актуальные проблемы современной науки, № 4, 2013 Медицинские науки Клиническая медицина Инфекционные болезни Абдуллина Н.Н., ассистент Ембергенова Ж.К., ассистент Мадреймова Ж.К., ассистент Гаипова Г.Т., ассистент (Нукусский филиал Ташкентского педиатрического медицинского института, Республика Узбекистан) Алланиязова Б.К., ассистент Нукусского медицинского колледжа №1 (Республика Узбекистан) ИЗМЕНЕНИЕ УРОВНЕЙ ПРОТИВОВОСПАЛИТЕЛЬНЫХ ЦИТОКИНОВ ПРИ ВИРУСНЫХ ДИАРЕЯХ У ДЕТЕЙ, ПРОЖИВАЮЩИХ В КАРАКАЛПАКСТАНЕ CHANGES IN THE LEVELS OF INFLAMMATORY CYTOKINES IN VIRUS DIARRHEA IN CHILDREN LIVING IN KARAKALPAKSTAN The negative impact of environmental factors on the health of the population has acquired a special significance for Karakalpakstan. <...> Duschanov B. and others (1998), mortality from intestinal infections in the region is high. <...> Dynamic observation of the children sick with acute intestinal infection in the recent years indicates a significant weighting of their clinical symptoms, increase the proportion of long-standing forms. <...> Probably, the causes of the identified features are not only a change in the etiological structure of diseases, worsening premorbid background of children and families social level, but also a change in immunological reactivity of the organism of a sick child. <...> The progress of immunology in the recent years shows that normally, many organs including the intestinal mucosa are in a condition of "controlled" inflammation, controlled by complex balance of proinflammatory and anti-inflammatory cytokines. <...> The aim of the study was to assess the levels of proinflammatory cytokines in viral diarrhea at children living in Karakalpakstan. <...> Materials and methods: The study involved 26 children with diarrhea caused by viral infection at the age of 6 months up to 3 years <...>