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Репродуктивное здоровье. Восточная Европа  / №1 2016

Flow phenomena of experimentally induced endometreosis in rats during the immunocorrection with a metabolic immune response modifi er 5-amino-1,2,3,4tetrahydrophthalazine-1,4-dione of sodium salt (30,00 руб.)

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Первый авторMalanchuk
АвторыKrasnianska L.
Страниц5
ID476078
АннотацияThe results of the experimental observation of the metabolic immune response modifi er 5-amino-1,2,3,4-tetrahydrophthalazine-1,4-dione of sodium salt impact on endometriosis genitalis externa in 50 scrub rats are ref elcted in the article. It is established that immunocorrective therapy held by metabolic immune response modifi er in female rats with endometreosis provides a recovery of a sexual cycle and improves the experimental disease procedure
Malanchuk, L. Flow phenomena of experimentally induced endometreosis in rats during the immunocorrection with a metabolic immune response modifi er 5-amino-1,2,3,4tetrahydrophthalazine-1,4-dione of sodium salt / L. Malanchuk, L. Krasnianska // Репродуктивное здоровье. Восточная Европа .— 2016 .— №1 .— С. 88-92 .— URL: https://rucont.ru/efd/476078 (дата обращения: 22.05.2022)

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Горбачевского, Тернополь, Украина Flow phenomena of experimentally induced endometreosis in rats during the immunocorrection with a metabolic immune response modifi er 5-amino-1,2,3,4tetrahydrophthalazine-1,4-dione of sodium salt Особенности протекания экспериментальн оиндуцированного эндометриоза у крыс при иммунокоррекции метаболическим иммуномодулятором 5-амино-1,2,3,4тетрагидрофталазин-1,4-дион натриевой соли ______________________ Abstract __________________________________________________________________________ The results of the experimental observation of the metabolic immune response modifi er 5-amino-1,2,3,4-tetrahydrophthalazine-1,4-dione of sodium salt impact on endometriosis genitalis externa in 50 scrub rats are refl ected in the article. <...> It is established that immunocorrective therapy held by metabolic immune response modifi er in female rats with endometreosis provides a recovery of a sexual cycle and improves the experimental disease procedure. <...> Среди категории лиц, страдающих синдромом тазовых болей, эндометриоз обнаруживают в 38,8%, а среди женщин с бесплодием – в 50% случаев. <...> Многими авторами доказано, что эндометриоз является только гинекологическим проявлением системной патологии, в основе которой лежит дисрегуляция различных иммунных и гормональных процессов. <...> One of the modern immune response modifi ers is 5-amino-1,2,3,4-tetrahydrophthalazine-1,4-dione of sodium salt. <...> The medicine guarantees the antioxidant eff ect and has anti-infl ammatory property, which infl uence positively on the course of the disease. <...> The aim of our work was to examine the impact of the metabolic immune response modifi er 5-amino-1,2,3,4-tetrahydrophthalazine-1,4-dione of sodium salt on the peculiarities of estrous cycle and the organic symptoms of endometreosis in rats during the experiment. <...> MATERIALS AND METHODS The experiment on 50 white female rats was carried out. <...> The scheme of the experimental model of endometreosis included autotransplantation of the left uterine horn fragments to the internal surface of the uterus in such a way that the endometrium was turned to the abdominal cavity. <...> The investigated animals were divided into two groups: the main group consisted of 25 scrub female rats with experimentally induced endometriosis, which were given hypo of 5-amino-1,2,3,4-tetrahydronaphthalene-1,4dionesodium salt dosed by 2 mg/kg per day in 1ml in physiological solution during 15 days; the control group included 25 scrub female rats with experimental endometreosis. <...> The animals were given hypo in equivalent amount of physiological solution during 15 days. <...> The medical treatment with the use of proposed immunomodulatory started in 4 <...>