Purpose: To analyze ndings of uorescent diagnostics in patients with vulva diseases. <...> Materials and methods: 83 patients with dystrophic processes, precancer and cancer processes in the vulva have been taken into the study. <...> The vulvoscopy revealed Lichen sclerosis in 35 patients (pathologic changes all over the vulva surface), squamous cell hyperplasia in 33 patients (64 foci), suspected dysplasia and initial vulva cancer in 15 patients (35 foci). <...> After histological examination the primary diagnosis was con rmed in 26 patients (54 foci), in 4 patients (6 foci) – VIN I–III and in 3 patients (4 foci) –cr in situ of the vulva stage I. There have not been revealed any additional uorescent foci on the surface of unchanged skin under the white light in patients with squamous cell hyperplasia. <...> In 15 patients with suspected dysplasia and initial cancer 35 foci, visualized in the white light, have been revealed. <...> Besides, 10 foci of additional uorescence invisible in the white light were revealed too. <...> Under the planned histological examination VIN I–III and Cr in situ of the vulva stage I were found in 35 foci under the white light and squamous hyperplasia – in 4 foci of additional uorescence in other 6 foci. <...> Effects of various femtosecond doses of laser irradiation (wavelength 1.55 m) at donors’ erythrocytes and neutrophils has been assessed in experiment in vitro. <...> It has been found out that femtosecond laser irradiation is a dose-dependent process which changes morphofunctional state in neutrophils and erythrocytes. <...> ФД у 35 пациенток со склеротическим лишаем выявила 45 очагов яркой флюоресценции, из них гистологически диагноз СЛ подтвержден в 35 очагах у 30 больных, диагноз VIN I–III выявлен в 10 очагах у 5 больных. <...> ГИ подтвердило диагноз ПГ в 54 очагах у 26 больных, в 6 очагах у 4 больных VIN I–III, в 4 очагах у 3 больных - cr in situ/щк вульвы I стадии. <...> У15 пациенток с подозрением на дисплазию и начальный <...>