K.I. Skryabina, Moscow, 109473 Russia, e-mail kazagor@gmail.com; , Kolpino, St. Petersburg, 192288 Russia, e-mail ilnikonov@yandex.ru Abstract Preservation of national gene pool requires the maintenance of quality standards of life including healthy nutrition. <...> In this relation there is a particular public concern about the use of antibiotic growth promoters (AGPs) as an essential part of intensive technologies of animal production, the remnant of the past when it was a commonplace. <...> WHO reported the constant growth of microbial resistance partly due to the transfer of AGPs into animal food products; it could enhance the distribution of bacteria resistant to antibacterial drugs and drug-resistant diseases hazardous for human race. <...> This hazard is probably underestimated as a result of the lack of knowledge on composition and possible changes in animal and human microbiome including microorganisms undetectable by classic microbiological methods but forming the basis of the microbiota. <...> Another underestimated possibility is the transfer of beneficial biologically active substances to human via animal food products when undesirable ingredients of animal feeds are simply substituted by harmless and biologically active ones, while more costly approaches to production of functional animal foodstuffs are widely discussed. <...> In our trials conducted on 3 groups of Cobb-500 broiler chicks (from 1 to 35 days of age) the possibility of substitution of feed additive Vinivet for AGPs in diets for broiler chicks was studied. <...> This additive based on apicultural products, i.e. bee-bread (ambrosia) and slumgum, was produced by no-waste technology (JSC Rusoborotexport, Kazan, Russia) preserving biologically active compounds from these products. <...> It was found that inclusion of Vinivet into broiler diets (5000 ppm) improved live bodyweight in group 3 compared to control group 1 (no Vinivet) by 0.61 and 0.86 % at 28 and 35 days of age, respectively; feed conversion rate (FCR) in group 3 was better by 3.15 % compared to control. <...> AGP Stafac 110 (Phibro Animal Health Corp., USA) fed to group 2 (180 ppm) was found to improve growth rate of broilers compared to groups 1 and 3. <...> The analysis of intestinal microbiota with the use of T-RFLP (Terminal Restriction Fragment Length Polymorphism) method showed substantial decline <...>