ТЕЗИСЫ IX СЪЕЗДА ОНКОЛОГОВ И РАДИОЛОГОВ СТРАН СНГ И ЕВРАЗИИ Выводы 1. <...> Плазмин блокирован α2-антиплазмином в ПЗ М в большей степени, чем в остальных тканях, т.е. в последних оставалось больше свободного плазмина. <...> Stereotactic Radiosurgery Center Sigulda, Sigulda, Latvia Hypofractionated radiosurgery treatment for cranial and extracranial tumors Objective. <...> High-precision radiation therapy is the modern standard of radiation oncology. <...> Hypofractionated stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) is the method of precise delivery of high doses of radiation for the cranial and extracranial lesions with limited radiation exposure to surrounding healthy tissue. <...> The CyberKnife M6™ delivers SRS and SBRT, with extreme accuracy over a minimum number of treatments, reducing side effects and preserving patients’ quality of life. <...> 15 patients had CyberKnife M6™ hypofractionated radiosurgery (SRS/SBRT) treatment in SRC «Sigulda» from December 2015. <...> There were 11 patients with cranial tumors (meningioma – 5 patients, acoustic shwanoma – 3 patients, brain metastasis – 3 patients), 1 patient with uveal melanoma, 1 patient with intramedullary spinal tumor, 2 patients with prostate cancer. <...> Each patient receives from 1 to 6 fractions of radiosurgical treatment (an average of 3.44 fractions per patient). <...> There were not acute post radiation complications and no local progression for this 3 month. <...> Partial tumor reduction was in 3 patients, stabilization of tumor size was in another 8 patients with cranial tumors and stabilization of tumor size was for extracranial tumors. <...> Conclusions: CyberKnife M6™ radiosurgery is a highly effective and safe treatment for patients with cranial and extracranial tumors, which allows you to keep a high level of quality <...>