Оригинальные исследования УДК: 616.132.2-089.168.1-06:616.61-008 Shafranskaya K., Zykov M., Bykova I., Kashtalap V., Kuzmina O., Ivanov S., Sumin A., Kutikhin A., Barbarash O. Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia Шафранская К. <...> Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний, Кемерово, Россия Рreoperative renal dysfunction is associated with an adverse in-hospital and long-term outcome after cabg surgery Предоперационная почечная дисфункция связана с неблагоприятным госпитальным и отдаленным исходом после аортокоронарного шунтирования ______________________ Abstract __________________________________________________________________________ long-term outcome after coronary artery bypass graft (CABG) surgery in patients with and without preoperative renal dysfunction [RD, defi ned as glomerular fi ltration rate (GFR) <60 ml/min/1.73 m2 We carried out this study with the aim to compare the prevalence of an adverse in-hospital and ]. <...> We recruited 720 consecutive Caucasian (Russian) patients who underwent CABG surgery in 2011– 2012. <...> Before the surgery, we measured serum creatinine concentration along with the calculation of GFR (MDRD formula) and risk of hospital death (EuroSCORE). <...> Preoperative GFR<60 ml/min/1.73 m2 stenosis of extracranial arteries and lower extremity arteries, adverse in-hospital cardiovascular and renal outcomes compared to GFR ≥60 ml/min/1.73 m2 GFR<60 ml/min/1.73 m2 was signifi cantly associated with a recurrent angina and progression of chronic heart failure. <...> In addition, combined adverse outcome after one year of follow-up was signifi cantly more frequent in a medium risk group (EuroSCORE 3–5) with a preoperative GFR<60 ml/ min/1.73 m2 . <...> Therefore, RD is signifi cantly associated with an adverse in-hospital and long-term outcome after CABG surgery. <...> Keywords: CABG surgery, renal dysfunction, glomerular fi ltration rate, prognosis, adverse outcome. ______________________ Резюме __________________________________________________________________________ Данное исследование было проведено с целью сравнения распространенности неблагоприятного госпитального и отдаленного исхода после аортокоронарного шунтирования (АКФ) у пациентов с и без почечной дисфункции [ПД, определяемая как скорость клубочковой фильтрации (СКФ) <60 мл/мин/1,73 м2 была статистически значимо ассоциирована с повышенwas signifi cantly associated with a higher <...>