Энтеровирусы человека под190 Инфекция и иммунитет разделяются на 4 вида (Human enterovirus A–D). <...> В работе мы рассматриваем вид энтеровирус A (HEV-A) как целое, а не отдельные серотипы, как это было принято в большинстве предшествующих работ. <...> Также мы изучали не отдельные рекомбинационные события, а динамику глобального пула генетической информации вида HEV-A. <...> Частота рекомбинации у разных серотипов вида HEV-A разительно отличалась. <...> Возможно, что у энтеровирусов вида HEV-A наблюдаются две эволюционные стратегии: максимальная лабильность неструктурных белков вирусов Коксаки, свободно сочетающихся с любыми капсидными белками, и адаптация неструктурных белков ЭВ71 к структурным белкам естественного серотипа. <...> SURVEILLANCE AND MOLECULAR EPIDEMIOLOGY OF MMR DISEASES IN FINLAND I. Davidkin, M. Kontio National Institute for Health and Welfare, Helsinki, Finland Surveillance of particular infectious disease is essential when assessing a success and effectiveness of preventing measures, such as vaccinations against it. <...> Материалы международной конференции 2013, Т. 3, № 2 Since 1982, MMR vaccinations against measles, mumps and rubella have belonged to the national vaccination program in Finland. <...> For monitoring a progress of this goal an enhanced surveillance of measles, mumps and rubella was started along with the MMR vaccinations. <...> The active investigations of suspected measles, mumps and rubella cases showed a rapid decline in the incidence of all the three diseases soon after the launchment of the nationwide MMR vaccinations. <...> The high MMR vaccination coverage was reached in the end of 1980s and indigenous measles, mumps and rubella were eliminated by the mid of 1990s from Finland. <...> Therefore, case-based laboratory surveillance and molecular epidemiological investigations became necessary to provide the required data in the elimination setting. <...> Molecular epidemiological characterization of sporadic cases has helped to identify the sources of imported cases and revealed that different genotypes of these diseases were imported over time to Finland. <...> The two separate clusters were caused by the D4 genotypes of measles virus, imported from other European countries; while two other imported measles cases in the same year were caused by other genotypes (D8 and G3) of measles virus. <...> Enhanced laboratory <...>