Briketa, Minsk, 220003 the Republic of Belarus, e-mail Volykhina@rambler.ru A b s t r a c t Viral infections are not considered the most dangerous honeybee (Apis mellifera L.) diseases though being rather harmful. <...> Virus-caused honeybee pathologies are mainly symptomless (N.J. Dimmock et al., 1987; A.C.F. Hung et al., 1996), nevertheless, a rapid replication of the viruses can be triggered leading to clinical manifestation and even death of the insects (R. Singh et al., 2010). <...> In honeybee families a simultaneous circulation of several viruses can occur. <...> A bee (ABPV), deformed wing virus (DWV) in Europe, and Kashmir bee virus (KBV), Israeli acute bee paralysis virus (IABPV) and DWV in the United States seem to be related to honeybee family collapse. <...> In Austria, France and Denmark the DWV was found in 91, 97 and 57% of the apiaries surveyed; in the Czech Republic 31% of sampled bees were infected with DWV (note, other viruses in Austria and France were less frequent, i.e. 68 and 58%, respectively, for ABPV; 49 и 86% for sacbrood virus, SBV; 30 and 86% for black queen cell virus, BQCV; and 10 and 28% for chronic bee paralysis virus, CBРV) (D. Tentcheva et al., 2004; O. Berйnyi et al., 2006). <...> DWV predominated in the apiaries of all studied regions of Russia (A. Kalashnikov et al., 2012), and in Moscow Province only DWV and SBV were revealed. <...> DWV, a RNA virus with monocistronic genome, is a member of the genus Iflavirus (Iflaviridae family, Picornavirales) (G. Lanzi et al., 2006). <...> Its phylogenetic relationship with Kakugo virus (T. Fujiyuki et al., 2004; A. Rortais et al., 2006) has been confirmed. <...> The identity of the RNA nucleotide sequences of virus isolates from different geographic locations is 98-99 % (O. Berиnyi et al., 2007). <...> Its structural proteins VP1-3 are similar to the corresponding picornavirus structural proteins, while a low molecular weight protein VP4 is not found (G. Lanzi et al., 2006). <...> The viral <...>