Emmauss, Kalininskii Region, Tver’ Province, 170530 Russia, e-mail vniimz@list.ru A b s t r a c t Worldwide, the mineral fertilizers, because of their multiple negative effects, become less popular. <...> Therefore, more producers prefer to use biofertilizer and biological preparations for obtaining high crop yield with good quality. <...> Fertilizers fill the soil with additional material, while biologicals contribute to effective mobilization of soil organic matter and biota. <...> At All-Russian Research Institute of Reclaimed Lands (VNIIMZ) the КMN biofertilizer (multi-purpose compost) has been developed. <...> Advantage of the КMN as a base fertilizer lies in its high nutritional value, physiological, ecological and biogenic properties. <...> Also, a novel biological product, the LPB, have been developed. <...> It is characterized by the presence of physiologically relevant amounts of growth factors and energy sources in a combination favorable to the plant. <...> The LPB composition allows to maintain soil fertility and crop productivity. <...> In the present study, we evaluated the effectiveness of the KMN and LPB on the potato ( m L.) variety Zhukovsky and spring wheat ( L.) variety Irgina. <...> The micro plot tests were conducted in 2011-2013 on the experimental field of VNIIMZ (Tver’ Province). <...> With spring wheat, the KMN biofertilizer was used at a dose of 7 t/ha, and NPK dose was 300 kg/ha. <...> Biological product (LPB stock preparation) was diluted with tap water as 1:300, 1:500 and 1:1000 and applied at 0.1 l/m2 by spraying plants. <...> In wheat, a total yield, weight of 1000 grains, and the grain protein content were estimated. <...> With potato, only KMN (4 t/ha) was used as fertilizer. <...> Potato plants were treated with LPB three times (at sprouting, budding and flowering) by means of a hand sprayer. <...> Control potato plants were not treated with LPB. <...> The potato yield and the tuber distribution by size were estimated. <...> The intensity of redox processes in the soil was evaluated by the oxidative-reduction ratio (ORR) as the catalase to dehydrogenase activity rate. <...> Spraying spring wheat with 1:300 LPB solution at 0.1 l/m2, additionally to КMN application, resulted in the highest yield among all the studied variants (27.5 <...>